UI - 000087

AU - Sjostrom S

TI - The relationship between the pharmacokinetics and pharmacodynamics of spinal opioids.

Minireview based on a doctoral thesis. [Review]

AB - Spinal opioids have been used clinically since the late seventies to treat acute, traumatic, obstetric and

chronic pain. In this article the influence of the pharmacokinetics on the dynamics of intrathecal and epidural

opioid administration are discussed with reference to current knowledge. [References: 121]

SO - Upsala Journal of Medical Sciences 1988;93:101-120