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American Society for Action on Pain |
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UI - 000009 AU - Jorum E TI - Endogene opiater og deres rolle i smerte-opplevelsen. (Endogenous opiates' role in pain perception.) AB - IN: U Oslo, Nevrofysiologisk Inst, Norway LA: Norwegian AB: The recent discovery of morphine- like substances and their receptors in the CNS has resulted in further understanding of the complex phenomenon of pain. The endogenous opiates--the enkephalins and endorphins--are richly presented in brain structures involved in pain perception and emotional behavior. The physiological part played by these opiates seems to be pain relief in situations of fear and anxiety. Disturbances in the endogenous level of endorphins and enkephalins may result in chronic pain and psychiatric disorders. Acupuncture analgesia is produced by a rise in the brain level of opiates, most likely the endorphins, further activating the descending midline serotonin system from the raphe nuclei known to exert inhibitory effects on spinal pain transmission. (5 ref) (PsycLIT Database Copyright 1982 American Psychological Assn, all rights reserved) KP: endogenous opiates; pain perception AN: 68-00559 SO - Tidsskrift for Norsk Psykologforening 1981;18:565-570 |