UI - 000015

AU - Ollat H

TI - Traitement pharmacologique de la douleur neuropathique. / Pharmacological treatment of neuropathic pain

AB - IN: Association pour la Neuro-Psycho-Pharmacologie, Paris, France LA: French AB: Reviews the

recent literature on pharmacological treatment of neuropathic pain (i.e., chronic pain resulting from injury to

the peripheral nervous system and induced by functional changes in peripheral and central pathways). Drugs

currently prescribed for neuropathic pain are discussed in terms of their effectiveness, indications, and

mechanisms of action. Data are presented on the use of various antidepressants, opiates, and anticonvulsants

for different neuropathic pain syndromes (e.g., trigeminal neuralgia, diabetic neuropathy, and postherpetic

neuralgia). Preliminary data from new pharmacological approaches (e.g., capsaicin, local anesthetics, and

anti-inflammatory agents) are reviewed, and research recommendations are provided. (English abstract)

(PsycLIT Database Copyright 1993 American Psychological Assn, all rights reserved) KP: pharmacological

treatment & drug indications & mechanisms of action; chronic neuropathic pain resulting from peripheral

nervous system injury; research review AN: 30-86136

SO - Revue Neurologique 1992;148:521-53