UI - 000021

AU - Toro R

AU - Perez Infante M

TI - Treatment of chronic pain with LARQ 731, a new alternative to opiate analgesics

AB - IN: Inst Venezolano de los Seguros Sociales, Hosp General "Miguel Perez Carreno" Servicio de

Anestesiologia, Caracas, Venezuela LA: English AB: LARQ 731 (a drug combination of carisoprodol,

dipyrone, and salicylamide) was administered to 42 36-88 yr old patients with advanced cancer who

complained of severe pain and who required frequent medication with opiate analgesics. To test the

analgesic efficacy of the combination, the arm-cuff method was used before and after drug administration to

evaluate the pain threshold. A large increase in pain threshold after LARQ 731 administration was observed.

No significant changes were found in routine laboratory examinations, blood pressure, heart, or breathing

rate. (PsycLIT Database Copyright 1992 American Psychological Assn, all rights reserved) KP: carisoprodol

& dipyrone & salicylamide; analgesic efficacy & pain thresholds; 36-88 yr old cancer patients with severe

pain AN: 79-10330

SO - Current Therapeutic Research 1991;49:187-19