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Table 1
Age | N |
% |
10-19 | 15 |
8.9 |
20-29 | 28 |
16.6 |
30-39 | 31 |
18.3 |
40-49 | 24 |
14.2 |
50-59 | 34 |
20.1 |
60-69 | 22 |
13.0 |
70+ | 15 |
8.9 |
169 |
100.0 |
Sex | N |
% |
Male | 76 |
45.0 |
Female | 93 |
55.0 |
THC Group | N |
% |
Oral | 94 |
55.6 |
Inhaled | 75 |
44.4 |
Marijuana | N |
% |
Prior Use | 69 |
41.1 |
No Prior Use | 99 |
58.9 |
Tumor Stage | N |
% |
Local | 16 |
9.4 |
Regional | 28 |
16.6 |
Metastatic | 125 |
74.0 |
Tumor Site | N |
% |
Breast | 30 |
17.8 |
Ovary | 30 |
17.8 |
Lung | 17 |
10.1 |
Gastrointestinal | 11 |
6.5 |
Genitourinary | 27 |
15.9 |
Leukemia/Lymphoma | 37 |
21.9 |
Other | 17 |
10.0 |
Chemotherapy | N |
% |
Mild | 20 |
11.8 |
Moderate | 73 |
43.2 |
Severe | 73 |
43.2 |
Not Reported | 3 |
1.8 |
Group x Chemotherapy | N |
% |
Age |
Age |
Oral-mild | 8 |
4.8 |
45.8 |
19-64 |
Oral-moderate | 42 |
25.3 |
48.3 |
13-78 |
Oral-severe | 44 |
26.5 |
42.9 |
12-76 |
Inhaled-mild | 12 |
7.2 |
54.7 |
35-76 |
Inhaled-moderate | 31 |
18.7 |
42.2 |
17-73 |
Inhaled-severe | 29 |
17.5 |
35.7 |
16-73 |
Table 1. Frequencies and descriptive statistics of selected variables.
TABLE 2
N |
SEX |
AGE |
AGE x SEX |
|||
M |
F |
M |
F |
|||
Oral | 94 |
39 |
55 |
45.6 yrs |
39.1 |
50.2 |
Inhaled | 75 |
37 |
38 |
41.9 yrs |
37.2 |
46.9 |
CHEMOTHERAPY SEVERITY |
PRIOR USE |
||||
Mild |
Moderate |
Severe |
No |
Yes |
|
Oral | 8 |
42 |
44 |
68 |
26 |
Inhaled | 12 |
31 |
29 |
31 |
43 |
CANCER STAGE |
|||
Local |
Regional |
Metastatic |
|
Oral | 11 |
11 |
72 |
Inhaled | 5 |
17 |
53 |
Table 2. Oral versus inhaled groups: descriptive variable comparison
TABLE 3
NAUSEA |
VOMITING |
|||
TIME | Mean |
(SD) | Mean |
(SD) |
0 Baseline | 4.53 |
(0.73) | 4.26 |
(1.04) |
1 Pre-THC | 2.26 |
(1.39) | 1.67 |
(1.27) |
2 Post-THC | 2.03 |
(1.22) | 1.73 |
(1.24) |
Time 1 - Time 0 | -2.25 |
(1.52) | -2.56 |
(1.58) |
Time 2 - Time 0 | -2.50 |
(1.32) | -2.52 |
(1.46) |
(Time 2 - Time 0) vs Group |
||||
Oral |
-2.46 |
-2.40 |
||
Inhaled |
-2.54 |
-2.69 |
||
(Time 2 - Time 0) vs Chemotherapy
Severity |
||||
Mild |
-2.76 |
-2.59 |
||
Moderate |
-2.77 |
-2.84 |
||
Severe |
-2.14 |
-2.19 |
||
(Time 2 - Time 0) vs Prior Use |
||||
Prior Use |
-2.39 |
-2.42 |
||
No Prior Use |
-2.56 |
-2.60 |
||
(Time 2 - Time 0) vs Randomization |
||||
Randomized |
-2.57 |
-2.55 |
||
Non-Randomized |
-2.47 |
-2.51 |
Table 3. Means and standard deviations of pertinent variables.
EUPHORIA |
SLEEPY |
AGITATION |
||||||||||
Time | No |
Yes |
? |
No |
Yes |
? |
No |
Yes |
? |
|||
0 | 142 |
4 |
2 |
59 |
28 |
61 |
124 |
21 |
3 |
|||
1 | 78 |
67 |
3 |
38 |
52 |
58 |
131 |
14 |
3 |
|||
2 | 81 |
64 |
3 |
27 |
68 |
53 |
126 |
19 |
3 |
|||
3 | 98 |
47 |
3 |
40 |
54 |
54 |
136 |
9 |
3 |
|||
4 | 94 |
27 |
27 |
34 |
42 |
72 |
115 |
5 |
28 |
|||
DEPRESSION |
FEARFUL |
ANXIOUS |
||||||||||
Time | No |
Yes |
? |
No |
Yes |
? |
No |
Yes |
? |
|||
0 | 122 |
24 |
2 |
123 |
22 |
3 |
80 |
65 |
3 |
|||
1 | 141 |
4 |
3 |
136 |
9 |
3 |
115 |
30 |
3 |
|||
2 | 136 |
9 |
3 |
139 |
6 |
3 |
118 |
26 |
4 |
|||
3 | 140 |
5 |
3 |
139 |
5 |
4 |
128 |
16 |
4 |
|||
4 | 113 |
3 |
29 |
115 |
4 |
29 |
106 |
13 |
29 |
Table 4. Side effect frequencies derived from patients responding to at least four of the five times assessed. Time 0 = Pre-THC; 1-4 is one to four hours post-THC.
Bryan A. Krumm
New Mexicans for Compassionate Use
phone (505) 286-1325
email krummb@unm.edu
internet http://www.livelinks.com/nmcu/
P.O.Box 4241
Albuquerque, N.M. 87196-4241