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American Society for Action on Pain

UI - 000007

AU - Ehrenpreis S

TI - D-phenylalanine and other enkephalinase inhibitors as pharmacological agents: Implications for some

important therapeutic applications

AB - IN: University of the Health Sciences/Chicago Medical School LA: English AB: Dextrophenylalanine

has proven to be beneficial in many human patients with chronic, intractable pain and is anti-inflammatory as

well. It is suggested that the enkephalinase inhibitors may be effective in a number of human "endorphin

deficiency diseases" such as depression, schizophrenia, convulsive disorders, and arthritis. Such compounds

may alleviate other conditions associated with decreased endorphin levels, such as opiate withdrawal

symptoms. (57 ref) (PsycLIT Database Copyright 1984 American Psychological Assn, all rights reserved)

KP: dextrophenylalanine & enkephalinase inhibitors; treatment of chronic pain & endorphin deficiency

diseases & opiate withdrawal symptoms AN: 71-10228

SO - Acupuncture and Electro Therapeutics Research 1982;7:157-172