Part I: Fundamentals of Pharmacology
Choosable Items of this Part:
2.1 Definition and certain characteristics of Ligands at the Opioid-receptors
9 Relevance of the Pharmacological Basics
9.1 Invasion: ‘Flash’ and ‘Sensation of Flooding’
9.2 Evasion: Sensation of Changes During the Day and Steady-State
2 Pharmacodynamics
2.1 Definition and certain characteristics of Ligands at the Opioid-receptors
2.2 Synapsis
2.3 Types of receptors
2.4 Localisation of Opioid-receptors
2.5 Specifity of Opioid-receptors
2.6 Functions of Opioid-receptors
2.7 Caracteristics of Opioid-receptors
2.8 Relative Intrinsic Activity (RIA)
2.9 Dose-Effect Relation
3 Pharmacokinetics
3.1 Absorption
3.2 Distribution, Blood-Brain-Barrier
3.3 Course of the Concentration in the Blood plasma by Different Forms of Consumption
3.4 Metabolism of some Opioids
3.5 Half-Life-Time, Dose interval and Accumulation
3.6 Tolerance
4.1 Representation of Behaviour in the Rewarding System
4.2 The Rewarding System and its Transmitters
4.3 The Dopaminergic Pathway from the Midbrain to the Basis of the Forebrain
5 Effects and Side-effects of Opioids
5.1 Central effects of Opioids
5.2 Peripheral effects of Opioids on Smooth Muscular Tissues
5.3 Endocrine effects of Opioids
5.4 Immunological effects of Opioids
5.5 Effects of Opioids on Neonates
5.6 Diverse effects of Opioids
5.7 Histamine Reaction
6 Addiction
7 Withdrawal
8 Galenics
8.1 Solutions for Injection
8.2 Inhalation / Smoke
8.3 Pernasal Consumption / Snorting
8.4 Anal-Suppositoires, per Ano
8.5 Per Os
8.6 Sublingual
9 Relevance of the Pharmacological Basics
9.1 Invasion: ‘Flash’ and ‘Sensation of Flooding’
9.2 Evasion: Sensation of Changes During the Day and Steady-State
9.5 Forms of Application und galenical Products