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Chloral HydrateThe oldest of the hypnotic (sleep inducing) depressants, chloral hydrate was first synthesized in 1832. Marketed as syrups or soft gelatin capsules, chloral hydrate takes effect in a relatively short time (30 minutes) and will induce sleep in about an hour. A solution of chloral hydrate and alcohol constituted the infamous "knockout drops" or Mickey Finn." At therapeutic doses, chloral hydrate has little effect on respiration and blood pressure but, a toxic dose produces severe respiratory depression and very low blood pressure. Although chloral hydrate is still encountered today, its use declined with the introduction of the barbiturates. Travel back to the DRCNet Response to the DEA Home Page Travel back to the List of DEA Publications Travel back to the Drugs of Abuse Table of Contents Travel back to the Drugs of Abuse Depressants Chapter |